Bacterial vaginosis (BV) is an infection caused by changes in the normal flora of the vagina to the growth of anaerobic bacteria, accompanied by changes in vaginal secretions. BV is found to be 40% in pregnancy and causes preterm. BV screening is done by examining vaginal smears. Recommended BV therapy is clindamycin or metronidazole, but based on the results of several studies, the use of both drugs for a long time is not effective. The aim of the study was to analyze the use of probiotics as a complementary therapy for BV in pregnancy. The original research method for probiotic-related research as a complementary therapy for BV in pregnancy. The results of the review are obtained: (1) Probiotic or bacteriotherapy is recommended as a BV treatment for a long time; (2) Lactobacilli contained in probiotics keeps the vagina from microorganisms by producing hydrogen peroxide and bacteriocin; (3) The combination of Lactobacillus rhanosus GR-1 and Lactobacillus reuteri RC-14 and metronidazole can reduce the prevalence of BV; (4) Probiotics can prevent preterm labor, 81% reduce the risk of vaginal infections; (5) In vitro studies, Lactobacilli has the effect of inhibiting Group B Streptococcus and Lactobacillus in the vagina in pregnant women. Treatment of BV by using oral probiotic combinations of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 and metronidazole effectively inhibits streptococcus group B in pregnant women. Based on a review of some of the results of these studies, probiotics are effectively used as complementary therapies combined with metronidazole and klandimycin to treat BV in pregnancy.